Non-covalent self assembly controls the relaxivity of magnetically active guests

Non-covalent self assembly controls the relaxivity of magnetically active guests.

The relaxivity of a magnetically responsive Gd complex can be controlled by non-covalent molecular recognition with a water-soluble deep cavitand. Lowered relaxivity is conferred by a self-assembled micellar "off state", and the contrast can be regenerated by addition of a superior guest.

Revealing molecular self-assembly and geometry of non-covalent halogen bonding by solid-state NMR spectroscopy.

We report a new spectroscopic fingerprint of intermolecular contacts in halogen bond-driven self-assembling aggregates and a precise determination of intermolecular NI distances in microcrystalline samples.

How phosphorylation controls the self-assembly of vertebrate smooth and non-muscle myosins.

Vertebrate non-muscle and smooth muscle myosin molecules, like almost all other myosins, have two heads, each of which carries an essential and a regulatory light chain. The rest of the molecule forms a rod-like tail, and it is these tails which are responsible for the self-assembly of myosin at physiological ionic strength to form filaments. The heads project from the resulting filaments, form...

Gold nanoparticle self-assembly promoted by a non-covalent, charge-complemented coiled-coil peptide

Instant immunity through chemically programmable vaccination and covalent self-assembly.

The ability to instantly create a state of immunity as achieved in the passive transfer of hyperimmune globulin has had a tremendous impact on public health. Unlike passive immunization, active immunization, which is the foundation of vaccinology, is an anticipatory strategy with inherent limitations. Here we show that elements of active and passive immunization can be combined to create an eff...